What is 2-(2-Hydroxyethyl)pyridine CAS 103-74-2?
Synthesis method: In industry, it is mainly prepared by the addition reaction of 2-methylpyridine with formaldehyde. This process is usually carried out under nitrogen protection at approximately 125°C and under certain pressure for several hours, and then the pure product is obtained through vacuum distillation.
Main application: Its core value lies in being an intermediate for organic synthesis. In the field of medicine, it is a key intermediate for synthesizing the antihistamine drug Betahistine. In materials science, it can be used as a stabilizer for synthesizing gold nanomaterials, or for preparing polymer materials and surfactants. The hydroxyl groups and pyridine rings in its molecule provide multiple possible reaction sites for subsequent chemical modifications.
2-(2-Hydroxyethyl)pyridine CAS 103-74-2 Use
2-Hydroxyethylpyridine is a metabolite of the anti-dizziness drug betahistine.
Used for organic synthesis.
2-(2-Hydroxyethyl)pyridine CAS 103-74-2 safety
Health hazard: This substance is irritating to the eyes, respiratory system and skin. Direct contact and inhalation of its vapor should be avoided.
Personal protection: During operation, appropriate protective equipment such as protective gloves, goggles and protective clothing must be worn.
Operating environment: Ensure that the workplace has good ventilation. It is best to perform the operation in a fume hood.
Storage requirements: It should be stored in a sealed manner in a cool, ventilated, and dry place, away from fire sources and heat sources, and be kept separate from oxidants. Due to its hygroscopic nature, the container must be kept tightly closed to prevent water absorption.
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