2-Chlorocinnamic acid CAS 3752-25-8
2-Chlorocinnamic acid CAS 3752-25-82-Chlorocinnamic acid CAS 3752-25-8

2-Chlorocinnamic acid CAS 3752-25-8

2-Chlorocinnamic acid CAS 3752-25-8

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O-chlorocinnamic acid (C₉H₇ClO₂) is a cinnamic acid derivative containing chlorine substituents, which has both the aromatic properties of cinnamic acid and the chemical activity of chlorine atoms. It has a unique aroma (similar to woody-spicy notes) and functionality, and is mainly used in daily chemicals, medicine and industrial synthesis.

3752-25-8

C9H7ClO2

182.6

223-154-2

2-Chlorocinnamic acid Information

Chemical Name2-Chlorocinnamic acid
CAS
3752-25-8
EINECS223-154-2
Molecular FormulaC9H7ClO2
Molecular Weight182.6
Spice TypeSynthetic fragrance

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2-Chlorocinnamic acid Uses

O-chlorocinnamic acid (C₉H₇ClO₂) is a cinnamic acid derivative containing chlorine substituents, which has both the aromatic properties of cinnamic acid and the chemical activity of chlorine atoms. It has a unique aroma (similar to woody-spicy notes) and functionality, and is mainly used in daily chemicals, medicine and industrial synthesis.


I. Daily chemicals and personal care


Flavor and fragrance ingredients

Perfume and fragrance: As a mid- and back-tone fragrance, it provides warm woody and spicy notes, and is often used in men's perfumes or oriental perfumes to enhance the layering and persistence of the fragrance.

Cleansing products: Add a small amount to soaps and shower gels to mask the chemical smell of cleaning ingredients and give the product a subtle balsamic scent.


Antibacterial and antiseptic

Use its antibacterial properties (effective against some Gram-positive bacteria) to add it to cosmetics or skin care products to extend the shelf life (the concentration must be controlled to ≤0.2%).


II. Medicine and Pharmaceuticals


Drug Synthesis Intermediates

Used in the synthesis of nonsteroidal anti-inflammatory drugs (such as clofenac compounds), antifungal drugs or cardiovascular drugs (chlorine atoms can enhance the activity of molecules).


Topical Agents

Laboratory studies have shown that it can inhibit skin inflammatory reactions or be used in anti-acne ointments (further clinical verification is required).


III. Industry and Chemicals


Organic Synthesis Raw Materials

Preparation of polymer materials: used for modification of polyester resins or ultraviolet absorbers (chlorine atoms enhance material stability).


Photosensitive Materials and Dyes

As a photoinitiator component, it is used in UV-cured coatings or inks (chlorine atoms improve the efficiency of photoreaction).

Synthetic azo dye intermediates to give fabrics light-resistant and wash-resistant properties.

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2-Chlorocinnamic acid Properties

Melting point
208-210 °C
Boiling point260.71°C
Density1.2377
StorageRoom temperature.
Water solubilityInsoluble in water
pKa4.23(at 25℃)


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