Acetyl Bromide CAS 506-96-7

Acetyl Bromide CAS 506-96-7 Information

CAS	506-96-7
Molecular formula	C2H3BrO
Molecular weight	122.95
EIENCS	208-061-7
Form	Fuming Liquid
Melting point	-96 °C
boling point	75-77 °C(lit.)
Density	1.663 g/mL at 25 °C(lit.)
Solubility	Miscible with ether, chloroform, benzene and acetone.
PKA	/
Color	Clear colorless to dark yellow
Storage temp

What is Acetyl Bromide CAS 506-96-7?

Acetyl bromide (CAS 506-96-7) is a highly active acyl halide reagent:

Irreplaceable acetylation ability: A key intermediate in the synthesis of pharmaceuticals, pesticides and high-end materials, with a reaction efficiency higher than that of acetyl chloride.

High Risk of operation: Highly corrosive, flammable, explosive upon contact with water 💥 Strict protection (fume hood + anti-corrosion equipment);

Industrial cost performance: Industrial grade (≥98%) with a price as low as ¥15/kg, suitable for bulk purchasing.

Acetyl Bromide CAS 506-96-7 Use

Organic synthesis

Acetylation reagent: Efficiently introduces acetyl groups (-COCH₃) and is used in the synthesis of esters, ethers, ketones and amide compounds.

Pharmaceutical intermediates: Preparation of anti-cancer drugs (hydroxyurea), sulfonamide drugs (sulfamethoxazole), and pesticides (methomyl).

Industrial application

Dye manufacturing: Synthesizing dye intermediates such as indigo.

Material modification: Monomers of polymer materials (such as polycarbonate).

Analytical Chemistry

Chromogenic reagents for detecting aldehydes and ketones. Alkalis, alcohols.

Acetyl Bromide CAS 506-96-7 safety

Hazardous characteristics:

Strong corrosiveness: Burns may occur upon contact with skin, eyes or respiratory tract (Risk Indication: R34).

Flammability: Flash point 75℃, vapor mixed with air can form explosive mixtures (UN 1716, Hazardous Materials Class 8/PG II).

Highly toxic decomposition products: When heated, it decomposes to release hydrogen bromide and highly toxic carbamoyl bromide (COBr₂).

Toxicity data:

Abdominal LD₅₀ in mice: 250 mg/kg (moderately toxic); Inhalation of LD₅₀ in mammals: 48 g/m³.

Protective measures:

When operating, wear anti-corrosion gloves, goggles and gas masks, and carry out the operation in a fume hood.

Leakage treatment: Adsorb with sand or dry lime. Do not rinse with water (reacts violently with water).

Storage requirements:

Keep sealed, dark, cool and well-ventilated (<30℃), away from oxidants, alkalis and alcohols.

Deshangchemical Info

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