2-Amino-3-Hydroxypyridine CAS 16867-03-1, 2-Amino-3-Hydroxypyridine, CAS 16867-03-1
Alternative names: 3-hydroxy-2-aminopyridine, 2-amino-3-pyridinol (commonly found in supplier documentation)
16867-03-1
C5H6N2O
110.11
240-886-8
| CAS | 16867-03-1 |
| Molecular formula | C5H6N2O |
| Molecular weight | 110.11 |
| EIENCS | 240-886-8 |
| Form | Crystalline Powder |
| Melting point | 168-172°C |
| boling point | 206.4°C |
| Density | 1.2111 |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| PKA | 5.15±0.10(Predicted) |
| Color | Grayish-beige to brownish |
| Storage temp | Keep in dark place,Sealed in dry,Room Temperature |
Molecules and Structures
Molecular formula: C₅H₆N₂O
Molecular weight: 110.11-110.12
Alternative names: 3-hydroxy-2-aminopyridine, 2-amino-3-pyridinol (commonly found in supplier documentation)
Appearance
High purity: Off-white crystals or white powder (≥99%)
Industrial grade: Light yellow to brown solid (affected by oxidation)
Melting and boiling points
Melting point: 170-176°C (common range in literature)
Boiling point: 385.2°C (760 mmHg)
Physicochemical parameters
Solubility: Readily soluble in water (263 g/L), methanol; Slightly soluble in chloroform
Stability: It has strong hygroscopicity and should be stored in a sealed container away from light. Long-term exposure is prone to oxidation and discoloration
Hazard Identification
UN 2811 (Class 6.1 toxic substance), R25 (toxic if swallowed), R36/37/38 (irritating to eyes/respiratory tract/skin)
Pharmaceutical synthesis
Core uses: A key intermediate for anti-AIDS drugs (such as protease inhibitors) and prostaglandin synthase inhibitors
Derivative development: It is used for the synthesis of antipyretic and analgesic drugs (such as acetaminophen analogues), antibacterial drugs and anti-tumor compounds
Industry and daily chemicals
Dye industry
Hair dye components (diazo dye precursors)
Dyeing intermediates for wool and polyamide fibers
Pesticides and Veterinary Drugs: Synthetic insecticide methylpyridinium
Scientific research application
Construct nitrogen-containing heterocyclic compounds, such as 2-(BOc-amino) -3-hydroxypyridine, for polypeptide modification
Health risk
Acute toxicity: Oral LD₅₀=301 mg/kg in rats, inhalation of dust causes respiratory tract damage
Chronic exposure: Long-term exposure may cause abnormal liver and kidney functions (IARC has not confirmed carcinogenicity).
Operation protection
Essential equipment: Gas mask, chemical protective suit, acid-resistant gloves and goggles (Safety terms: S26/S36/S37)
Leakage treatment: After adsorption by sand and soil, transfer to hazardous waste disposal. Do not use water flushing (to avoid diffusion).
Storage requirements
Seal and keep away from light. Cool and dry (≤25℃), away from oxidants and strong acids
* Prompt reply and 24 hours online, professional team to provide best price and high quality product.
* Sample testing support.
* Every batch of products will be tested to ensureits quality.
*The packing also can be according the customers` requirment.
*Any inquiries will be replied within 24 hours.
*we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.
Service Hotline
