4-Chloro-2-Bromoacetophenone CAS 536-38-9, 4-Chloro-2-Bromoacetophenone, CAS 536-38-9
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4-chloro-2 '-bromoacetophenone (CAS 536-38-9) is a highly active halogenated aryl ketone, and its core value lies in:Synthetic versatility: As a key intermediate for pharmaceuticals, pesticides and flame retardants, it can construct complex molecular chains through functional group transformation.
536-38-9
C8H6BrClO
233.49
208-631-5
| CAS | 536-38-9 |
| Molecular formula | C8H6BrClO |
| Molecular weight | 233.49 |
| EIENCS | 208-631-5 |
| Form | Crystals |
| Melting point | 93-96 °C(lit.) |
| boling point | 186°C (rough estimate) |
| Density | 1.5624 (rough estimate) |
| Solubility | soluble in Methanol |
| PKA | / |
| Color | White to pale yellow |
| Storage temp |
4-chloro-2 '-bromoacetophenone (CAS 536-38-9) is a highly active halogenated aryl ketone, and its core value lies in:
Synthetic versatility: As a key intermediate for pharmaceuticals, pesticides and flame retardants, it can construct complex molecular chains through functional group transformation.
High operational risk: Strong lachrymatory and corrosive properties require strict protection. Storage should be kept away from light and refrigerated.
Industrial applicability: High-purity (≥98%) products can meet the demands of large-scale production, but attention should be paid to the stability of the supply chain.
Pharmaceutical intermediates
A key raw material for synthesizing drug molecules containing bromine/chlorine functional groups (such as antibiotics and anti-tumor compounds).
Pesticide synthesis
It is used for the preparation of brominated insecticides or fungicides, for example, by introducing sulfides or amino structures through nucleophilic substitution reactions.
Modification of polymer materials
As a precursor of flame retardants, it participates in the synthesis of brominated polymers to enhance the fire resistance of plastics and coatings.
Toxicity: Moderate toxicity (Oral LD₅₀ >2000 mg/kg in mice); Strong irritation (Burns caused by contact with eyes/skin)
Hazard Signs: R34 (Causes burns), R22 (Harmful if swallowed), R36 (Irritates eyes)
Safe operation: Wear protective clothing, goggles and gas masks; Operate in a fume hood
Storage conditions: Refrigerate away from light (2-8°C), sealed and dry. Keep away from oxidants and strong alkalis
Fire extinguishing measures: Use water mist, dry powder, foam or carbon dioxide fire extinguishers
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