3-Chloro-2-Methylpropene CAS 563-47-3
3-Chloro-2-Methylpropene CAS 563-47-33-Chloro-2-Methylpropene CAS 563-47-3

3-Chloro-2-Methylpropene CAS 563-47-3

3-Chloro-2-Methylpropene CAS 563-47-3, 3-Chloro-2-Methylpropene, CAS 563-47-3

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3-chloro-2-methylpropylene (CAS 563-47-3), as a highly active halogenated alkene, is a key intermediate in the synthesis of pesticides (phenyclotin, kebovir) and pharmaceuticals.

563-47-3

C4H7Cl

90.55

209-251-2

3-Chloro-2-Methylpropene CAS 563-47-3 Information

CAS 563-47-3
Molecular formula C4H7Cl
Molecular weight 90.55
EIENCS 209-251-2
Form Liquid
Melting point -80°C
boling point 71-72°C
Density 0.925 g/mL at 20°C
Solubility Insoluble in water; It is readily soluble in ethanol, carbon tetrachloride and ether
PKA /
Color Clear
Storage temp

3-Chloro-2-Methylpropene CAS 563-47-3

What is 3-Chloro-2-Methylpropene CAS 563-47-3?

3-chloro-2-methylpropylene (CAS 563-47-3), as a highly active halogenated alkene, is a key intermediate in the synthesis of pesticides (phenyclotin, kebovir) and pharmaceuticals. Its strong volatility, flammability, explosiveness and carcinogenicity require strict compliance with safety regulations (explosion-proof equipment, inert gas protection).


Chemical Name: 3-chloro-2-methylpropene (Also known as: methylallyl chloride, 2-methylallyl chloride, isobutylchloride)

Molecular formula: C₄H₇Cl

Molecular weight: 90.55 g/mol

CAS Number: 563-47-3

EINECS No. : 209-251-2


3-Chloro-2-Methylpropene CAS 563-47-3 Use

1. Pesticide Synthesis (Core Application

Acaricide intermediate: Chlorinated tert-butylbenzene, a key raw material for the synthesis of styrene-tin.

Insecticide intermediates: Furanol, an intermediate used in the production of Kebawei.

Other pesticides: Participate in the synthesis of herbicides such as methyl fluoxate.


2. Pharmaceuticals and Fine Chemicals

Pharmaceutical intermediates: synthetic reverse transcriptase viral protease inhibitors, muscone, etc.

Polymer additives: Production of sodium methylallyl sulfonate, 3-chloro-2-methylpropylene oxide.

Biomedical research: Reacts with isopropylamine to form N-isopropylmethylacrylamide, which is used as a drug carrier.


3. Other fields

Spice synthesis: Synthesis of high-value spice compounds.

Electronic materials: Participate in the preparation of special materials as organic synthesis reagents.


3-Chloro-2-Methylpropene CAS 563-47-3 safety

Health and environmental risks

Toxicity

Oral administration of LD₅₀ = 848 mg/kg in rats (poisoning); It is easily absorbed through the skin, causing burns and respiratory tract irritation.

Carcinogenicity: IARC classifies it as a Group 2B carcinogen (possibly carcinogenic to humans).

Environmental risk: Toxic to aquatic organisms. Leakage into water bodies must be prevented.


Operation and storage requirements

Protective measures

Wear a gas mask, acid and alkali resistant gloves, goggles and anti-static clothing.

Local exhaust ventilation should be provided to avoid contact with oxidants (which may cause combustion).


Storage conditions

Cool and well-ventilated place (≤30℃), protected by inert gas, isolated from oxidants.


Leakage Emergency response

Absorb with sand and soil. Do not rinse with water (it releases heat when exposed to water). When there is a large-scale leakage, the containment is carried out by building embankments and then burned.


Deshangchemical Info

  • ● Comgpany name : Shandong Deshang Chemicals Co., Ltd.
  • ● Main products : Treatments, sedimentation agents, flame retardants, catalysts, matte pigments, talcum powder, PVC additives, antifreeze agents, cellulose, cleaning agents, coconut oil, hydroxyethyl, cosmetics, matte agents, betaine, disinfectants, photosensitizers, humidifying agents, blue pigments, curing agents, potassium formate, sodium formate, cyclohexanol, preservatives, grinding aids.
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