Dextran CAS 9004-54-0 Information
| CAS |
9004-54-0 |
| Molecular formula |
C17H32O10 |
| Molecular weight |
396.42998 |
| EIENCS |
232-677-5 |
| Form |
Solid |
| Melting point |
483 °C (decomp) |
| boling point |
/ |
| Density |
/ |
| Solubility |
H2O: soluble50mg/mL, clear to very slightly hazy, colorless to faintly yellow |
| PKA |
/ |
| Color |
White to slightly off-white |
| Storage temp |
2-8°C |
What is Dextran CAS 9004-54-0?
Chemical name
Molecular formula: (C 6 H 10 O 5) n
The degree of polymerization n determines the molecular weight.
CAS Number: 9004-54-0
EINECS number: 232-677-5
Source and Structure
Natural sources: Mucus secreted by microorganisms (such as Enterostromyces intestinalis), plant cell walls.
Structural characteristics:
α -glucan: The main chain is connected by α-1,6 glycosidic bonds and contains α-1,3/α-1,4 side chains (such as dextran).
β -glucan: The main chain is connected by β-1,3 glycosidic bonds and contains β-1,6 side chains (such as yeast glucan).
Dextran CAS 9004-54-0 Use
1. Medicine and Clinical Practice
Plasma substitutes: Medium molecular weight Dextran (such as DEXtran 40/70) is used to expand blood volume and prevent shock.
Drug carrier: As a sustained-release material to encapsulate drugs and prolong therapeutic effects (such as the delivery of anti-cancer drugs).
Biological separation: Glucan gels (such as Sephadex®) are used for chromatographic purification of proteins and nucleic acids.
2. Food industry
Thickening stabilizer: Addition amount 0.1% - 1%, to improve the texture of bread and dairy products.
Functional health care: β -glucan regulates blood sugar and enhances immunity (such as from oats and yeast sources).
3. Cosmetics and Personal care
Moisturizing and repairing: β -glucan promotes the repair of the skin barrier and is used in essence and face cream (concentration 0.5% - 2%).
Antioxidant: Eliminate free radicals and delay skin aging.
4. Industry and Scientific Research
Biological protectants: Low-molecular-weight Dextran (such as Dextran 10) is used for cryopreservation of cells/organs.
Industrial additives: Papermaking adhesives, textile lubricants.
Dextran CAS 9004-54-0 safety
1. Security:
Low toxicity: Safe for oral administration (LD₅₀ > 15g/kg, rats).
Contraindications: People with severe coagulation disorders should avoid intravenous injection.
2. Storage conditions:
Keep sealed, away from light, in a cool and dry place (< 30℃).
Avoid strong acids and strong oxidants.
