Dextran CAS 9004-54-0, Dextran, CAS 9004-54-0
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Dextran (CAS 9004-54-0), as a multi-branched functional polysaccharide, has the core value of:Cross-border applications: spanning four major fields including medicine (plasma substitutes), food (functional additives), scientific research (chromatographic media), and industry (biomaterials).
9004-54-0
C17H32O10
396.42998
232-677-5
| CAS | 9004-54-0 |
| Molecular formula | C17H32O10 |
| Molecular weight | 396.42998 |
| EIENCS | 232-677-5 |
| Form | Solid |
| Melting point | 483 °C (decomp) |
| boling point | / |
| Density | / |
| Solubility | H2O: soluble50mg/mL, clear to very slightly hazy, colorless to faintly yellow |
| PKA | / |
| Color | White to slightly off-white |
| Storage temp | 2-8°C |
Dextran (CAS 9004-54-0), as a multi-branched functional polysaccharide, has the core value of:
Cross-border applications: spanning four major fields including medicine (plasma substitutes), food (functional additives), scientific research (chromatographic media), and industry (biomaterials);
Technology trends: Optimization of microbial fermentation processes to increase yield, development of gene-edited bacterial strains with high activity β -glucan;
Purchasing suggestions:
Industrial selection: ¥8-15/kg, industrial grade; Food/cosmetics: 70%+ purity β -glucan (oat/yeast source); Pharmaceutical preferred: EP/USP certified injection grade.
Industry prospects: The global market is expected to grow by 8% annually by 2025. China's production capacity will account for 40% of Asia's, and the demand for bio-based materials will drive innovation.
1. The field of medicine
Plasma expansion agent: Low molecular weight (Dextran 40/70) is used for shock treatment to maintain blood volume.
Drug carrier: As a sustained-release agent or targeted drug delivery carrier, it enhances the bioavailability of drugs.
Vaccines and Diagnostics: Used as an antigen stabilizer in vaccines or for the isolation of blood cells (such as Dextran 500).
2. Food industry
Functional additives: Thickener/stabilizer (addition amount 0.1-1%), used in dairy products, pastries and beverages.
Health benefits: β -glucan (derived from oats/yeast) can lower cholesterol and regulate blood sugar, making it a new resource food.
3. Scientific Research and Industry
Chromatographic separation: Cross-linked glucan gels (such as Sephadex G-15/G-25) are used for protein and DNA purification.
Industrial additives: Papermaking adhesives, thickeners for oil drilling, moisturizing ingredients for cosmetics (yeast β -glucan).
Toxicity: Actually non-toxic (oral LD₅₀ >5000 mg/kg in rats), but the injection may cause allergic reactions.
Regulatory restrictions:
Food additives must comply with the GB standard (for example, for baked goods, ≤55mg/kg).
Pharmaceutical injections need to be strictly treated aseptically to avoid endotoxin contamination.
Storage requirements: Store at room temperature, away from light and sealed. Shelf life: 2-3 years. The solution needs to be protected from the growth of microorganisms.
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