2,6-Dimethylaniline CAS 87-62-7, 2,6-Dimethylaniline, CAS 87-62-7
2, 6-dimethylaniline (CAS 87-62-7), as a high-value-added aromatic amine, is a core intermediate in the synthesis of pesticides and pharmaceuticals, especially leading the production of key products such as metalaxyl and lidocaine. Its strong toxicity, carcinogenicity and flammability must strictly comply with safety regulations (gas masks, inert gas protection).
87-62-7
C8H11N
121.18
201-758-7
| CAS | 87-62-7 |
| Molecular formula | C8H11N |
| Molecular weight | 121.18 |
| EIENCS | 201-758-7 |
| Form | Liquid |
| Melting point | 10-12°C |
| boling point | 216°C |
| Density | 0.984 g/mL at 25°C |
| Solubility | Insoluble in water; It is readily soluble in ethanol, ether and dilute hydrochloric acid |
| PKA | 3.89(at 25℃) |
| Color | Clear yellow to red-brown |
| Storage temp | / |
2, 6-dimethylaniline (CAS 87-62-7), as a high-value-added aromatic amine, is a core intermediate in the synthesis of pesticides and pharmaceuticals, especially leading the production of key products such as metalaxyl and lidocaine. Its strong toxicity, carcinogenicity and flammability must strictly comply with safety regulations (gas masks, inert gas protection).
Chemical Name: 2, 6-dimethylaniline (also known as 2, 6-dimethyl aniline, o-dimethylaniline)
Molecular formula: C₈H₁₁N
Molecular weight: 121.18 g/mol
CAS Number: 87-62-7
EINECS number: 201-758-7
1. Pesticide synthesis
● Fungicide intermediates: Production of highly efficient fungicides such as metalaxyl, benzoyl, furumyl, and metalaxyl.
● Herbicide intermediates: Used in the synthesis of low-toxicity herbicides such as isobutachlor and Trelledo (dimethyl chlor).
2. Medicine and Veterinary Drugs
● Synthesis of anesthetic drugs: Production of local anesthetics such as lidocaine hydrochloride and bupivacaine hydrochloride.
● Veterinary drug raw materials: Used in the production of the veterinary drug Jingsongling (sedative).
3. Other industrial uses
● Dye intermediate: As a precursor of aromatic amine dyes.
● Polymer additives: Additives involved in the synthesis of high-performance engineering plastics.
Health risk
Acute toxicity
Oral administration of LD₅₀ = 840 mg/kg in rats; Oral administration of LD₅₀ = 707 mg/kg in mice.
Methemoglobinemia: Inhibits the oxygen-carrying capacity of hemoglobin, leading to tissue hypoxia.
Carcinogenicity: Classified by the International Agency for Research on Cancer (IARC) as a Group 2B carcinogen (possibly carcinogenic to humans).
Exposure hazard:
Skin contact causes burns and dermatitis; Steam irritates the respiratory tract and may cause pulmonary edema.
Operation and storage specifications
Protective measures
Wear a gas mask, acid and alkali resistant gloves, goggles and a local exhaust system.
Leakage treatment
Collect after being adsorbed with sand and soil. Do not rinse with water (it releases heat when exposed to water).
Storage conditions
Store in a sealed container in a cool and well-ventilated place (≤30℃), isolated from oxidants and acids.
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