Hydroxypropyl Cyclodextrin CAS 128446-33-3 Information
| CAS |
128446-33-3 |
| Molecular formula |
/ |
| Molecular weight |
0 |
| EIENCS |
451-510-9 |
| Form |
Solid powder |
| Melting point |
245 °C (dec.)(lit.) |
| boling point |
/ |
| Density |
1.39 at 24.6℃ |
| Solubility |
Soluble in water, methanol, DMF. Insoluble in acetone, chloroform. |
| PKA |
/ |
| Color |
White to off white |
| Storage temp |
|
What is Hydroxypropyl Cyclodextrin CAS 128446-33-3?
Propyl -α -cyclodextrin (128446-33-3) has become a key functional excipient in the pharmaceutical, food and cosmetic industries due to its unique inclusion ability and low toxicity. When making a choice, pay attention to:
Pharmaceutical grade: Products with high substitution degree (MS≥1.5) and high purity (≥99%) are preferred.
Industrial grade: Cost-oriented, pay attention to the control of heavy metal residues.
Hydroxypropyl Cyclodextrin CAS 128446-33-3 Use
Pharmaceutical industry: Drug carriers (injections, oral preparations), improving the bioavailability of poorly soluble drugs, encapsulation and solubilization, sustained-release, and reducing toxic and side effects
Food industry: Stabilizers, emulsifiers (sauces, healthy beverages), extending shelf life, inhibiting oil oxidation, and improving taste
Cosmetics: Thickeners, moisturizing ingredients, enhancing the penetration of active ingredients, improving stability, and optimizing skin feel
Environmental protection and materials: Adsorbents for wastewater treatment, slow-release carriers for pesticides, chelating pollutants, and controlling release rates
Hydroxypropyl Cyclodextrin CAS 128446-33-3 safety
Toxicological data
Oral toxicity: Rat LD₅₀ >2,000 mg/kg, which belongs to the actual non-toxic level.
Irritation: No irritation to the skin or eyes (rabbit experiment).
Regulatory certification
It has been approved by the FDA for oral/injectable preparations and complies with GRAS standards.
Food grade must meet the limits of heavy metals (Pb≤20 ppm, As≤5 ppm).
