Icaridin CAS 119515-38-7 Picaridin, Icaridin, CAS 119515-38-7, Picaridin
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Chemical Name: Isobutyl hydroxyethyl piperidine carboxylate (or 2-(2-hydroxyethyl) piperidine 1-carboxylate sec-butyl)
119515-38-7
C12H23NO3
229.32
423-210-8
| CAS | 119515-38-7 |
| Molecular formula | C12H23NO3 |
| Molecular weight | 229.32 |
| EIENCS | 423-210-8 |
| Form | Oil |
| Melting point | <-170° |
| boling point | 2800C |
| Density | d20 1.07 |
| Solubility | Chloroform (Slightly), Methanol (Slightly) |
| PKA | 15.15±0.10(Predicted) |
| Color | Colourless |
| Storage temp |
1. Basic chemical information
Chemical Name: Isobutyl hydroxyethyl piperidine carboxylate (or 2-(2-hydroxyethyl) piperidine 1-carboxylate sec-butyl)
Alternative names: Icaridin, picaridin, hydroxypiperidate
Molecular formula: C₁₂H₂₃NO₃
Molecular weight: 229.32 g/mol
CAS Number: 119515-38-7
Appearance: Colorless, transparent and viscous liquid, without irritating odor
Solubility: Readily soluble in polar solvents such as water and ethanol, without greasiness.
2. Mechanism of Action and Efficacy
The principle of mosquito repellent
Picaridine interferes with the olfactory receptors of mosquitoes, blocking their perception of substances such as carbon dioxide and lactic acid released by the human body, thereby forming an "odor barrier" that prevents mosquitoes from locating the skin.
Protective performance
Broad-spectrum insect repellent: Effective against mosquitoes, ticks, flies, gnats, etc., and can prevent vector-borne diseases such as dengue fever, malaria, and Lyme disease.
Protection duration:
10% concentration: 3 to 5 hours
20% concentration: 8-14 hours (significantly superior to DEET and natural essential oils).
Environmental adaptability: The waterproof and sweat-proof formula is suitable for water or high-intensity activities.
Usage scenarios
Daily protection: For short outings (such as taking a walk), use a 10% concentration spray.
Outdoor activities: For camping, hiking and water activities, a 20% concentration is recommended, along with physical protection (mosquito nets, long sleeves).
Special requirements: Pregnant women and children are preferred to choose picaridin instead of DEET
Health safety
Skin irritation: No skin sensitization, no residue, suitable for sensitive skin and children (≥2 months old).
Toxicity comparison:
Oral LD₅₀ in rats was > 2,000 mg/kg (slightly toxic, safer than table salt).
Suitable for pregnant women: One of the few chemical mosquito repellents that can be safely used by pregnant women.
Non-corrosive: Does not damage plastic or leather products (DEET is prone to cause corrosion).
Environmental safety
It has high environmental compatibility and no aquatic toxicity (not rated by WGK), but large-scale discharge into water bodies should be avoided.
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