L-Proline CAS 147-85-3, L-Proline, CAS 147-85-3
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L-proline (CAS 147-85-3), as a key amino acid, with its unique cyclic structure, is irreplaceable in the fields of medicine (synthesis of antihypertensive drugs), food (flavor enhancement), agriculture (stress resistance regulation), and catalysis.
147-85-3
C5H9NO2
115.13
205-702-2
| CAS | 147-85-3 |
| Molecular formula | C5H9NO2 |
| Molecular weight | 115.13 |
| EIENCS | 205-702-2 |
| Form | powder |
| Melting point | 228 °C (dec.) (lit.) |
| boling point | 215.41°C (rough estimate) |
| Density | 1.35 |
| Solubility | H2O: 50 mg/mL |
| PKA | 1.95, 10.64(at 25℃) |
| Color | White |
| Storage temp | 2-8°C |
L-proline (CAS 147-85-3), as a key amino acid, with its unique cyclic structure, is irreplaceable in the fields of medicine (synthesis of antihypertensive drugs), food (flavor enhancement), agriculture (stress resistance regulation), and catalysis. Its high water solubility (>150g/100ml) and biocompatibility support cross-industry applications.
Usage note: Moisture absorption and caking should be avoided. Strictly distinguish between food-grade (GB 2760) and industrial-grade applications.
Purchasing suggestions:
Pharmaceutical research and development: Wuhan Tianzhi (high purity quality inspection) or TCI (cell culture grade) is preferred;
Food industry: Zhengzhou Aikemu (Compliant food grade, in stock)
Agriculture/Feed: Shenzhen Lefu (Cost-effective industrial grade, tonnage discount).
1️ Medicines and health products
Amino acid infusion: It supplements the protein of postoperative or malnourished patients and enhances tissue repair.
Antihypertensive drug intermediates: Synthesis of ACE inhibitors such as captopril and enalapril (core raw materials).
Joint health: Promotes cartilage healing and assists in the treatment of osteoarthritis (a key component of collagen).
2️ Food industry
Nutritional supplement: Added to beverages, dairy products and meat products, the dosage is usually ≤ 1.0g /kg (GB 2760 standard).
Flavor enhancer: When heated with sugar, it undergoes the Maillard reaction, generating a burnt aroma substance (such as in baked goods and condiments).
3️ Agriculture and Feed
Plant stress resistance agent: Enhances the drought and salt resistance of crops (osmotic regulation effect), with a spraying rate of 5-10 kg per hectare.
Feed additive: Enhance the growth performance of livestock and poultry (addition amount: 1-5 kg per ton of feed).
4️ Industrial catalysis
Asymmetric synthesis catalyst: Used in hydrogenation, polymerization and other reactions, with high stereoselectivity.
Health risk:
Irritates the eyes, skin and respiratory tract (GHS markings: H315, H319).
Oral LD50 for rats: 2130 mg/kg (moderately toxic).
Storage requirements:
Keep in a cool and dry place, sealed (≤37°C), and away from oxidants.
Protective measures: Wear gloves and goggles during operation.
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