N-Acetyl-Alpha-D-Glucosamine CAS 10036-64-3, N-Acetyl-Alpha-D-Glucosamine, CAS 10036-64-3
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N-acetyl -α -D-glucosamine (CAS 10036-64-3) is a multifunctional natural compound and is widely used in cosmetics (whitening, anti-aging), medicine (arthritis treatment) and the food industry.
10036-64-3
C8H15NO6
221.21
233-115-1
| CAS | 10036-64-3 |
| Molecular formula | C8H15NO6 |
| Molecular weight | 221.21 |
| EIENCS | 233-115-1 |
| Form | powder |
| Melting point | 211 °C |
| boling point | 595.4±50.0 °C(Predicted) |
| Density | 1.5 |
| Solubility | It is readily soluble in water but poorly soluble in organic solvents such as ethanol and propanol |
| PKA | 12.04±0.70(Predicted) |
| Color | White |
| Storage temp | Refrigerator (+4°C) |
N-acetyl -α -D-glucosamine (CAS 10036-64-3) is a multifunctional natural compound and is widely used in cosmetics (whitening, anti-aging), medicine (arthritis treatment) and the food industry. It has high safety and diverse sources (extracted from crustaceans or through biological fermentation), and especially under modern green processes, it can avoid the shortcomings of traditional methods.
NAG is a key monomer of polysaccharides (such as hyaluronic acid and chitin) in organisms and has multiple physiological functions:
Antioxidant property: It eliminates free radicals through hydroxyl and amino groups and inhibits lipid oxidation (the effect is more significant in aqueous media).
Joint health: Promotes the synthesis of cartilage matrix and is used as an adjunctive treatment for osteoarthritis and rheumatoid arthritis.
Skin efficacy:
Moisturizing: Increase the moisture content of the stratum corneum (clinically verified to show significant improvement within 8 hours).
Whitening: Inhibits tyrosinase activity (with significant effect at a concentration of 50 mg/mL) and reduces melanin production.
Anti-wrinkle: Promotes the synthesis of type I collagen (effective at 0.1-10 mg/mL).
Immune regulation: Enhance the activity of macrophages and assist in inhibiting tumor growth.
Application in cosmetics
NAG is an internationally recognized cosmetic ingredient (INCI name: Acetyl Glucosamine), and it has the following characteristics:
Suggested addition amount: 0.2% - 5% (Safe concentration ≤5%).
Compounding plan:
When compounded with nicotinamide (4%+2%), it can significantly fade pigmentation.
The combination of vitamin C and arbutin enhances the whitening effect.
Product types: essence, face cream, mask, foundation liquid, etc
Applications in the fields of medicine and food
Medications: Oral or topical preparations for the treatment of arthritis (such as joint application products).
Food additives
As an antioxidant and sweetener (suitable for diabetic patients).
Infant and toddler food additives promote intestinal health.
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