Poly(acrylic acid) CAS 9003-01-4 Carbopol C5H10O2
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Carbomer resin, also known as carbomer, is an acrylic acid cross-linked polymer with the appearance of a white powder. It has good thickening, system stabilization, suspension and active substance release functions and is widely used in personal care products, cosmetics, pharmaceuticals and oral care products.
9003-01-4
C5H10O2
102.1317
618-347-7
| CAS | 9003-01-4 |
| Molecular formula | C5H10O2 |
| Molecular weight | 102.1317 |
| EIENCS | 618-347-7 |
| Form | Powder |
| Melting point | 95 °C |
| boling point | 116 °C |
| Density | 1.2 g/mL at 25 °C |
| Solubility | Soluble in water. |
| PKA | / |
| Color | White |
| Storage temp | 2-8°C |
Carbomer is a general term for a class of cross-linked polyacrylic acid resins. It is a polymer compound formed by the polymerization of acrylic acid and has strong hydrophilicity and ion responsiveness. It is a very important synthetic polymer, known for its excellent thickening, suspension, stabilization and gel-forming abilities.
1. Thickener for personal cleansing products: This is one of its most widely used applications. Carbomer is added in large quantities to shampoos, shower gels, hand soaps and facial cleansers. Its main function is to increase the viscosity of the product and improve the sensory experience during use (such as easier application, less dripping) and appearance texture.
2. Gel product matrix: When the carbomer aqueous dispersion is neutralized with an appropriate base (such as triethanolamine, sodium hydroxide), it can form a clear, transparent or translucent gel. This makes it an ideal matrix for making a variety of transparent gels, such as:
Skin care gel: gel-like cream, moisturizing gel, after-sun repair gel.
Hair styling gel: Provides styling power without residue.
Shaving gel: Provides lubrication and a smooth shaving experience.
Hand sanitizer gel: Demand has surged especially during the epidemic.
3. Topical drug matrix: In the pharmaceutical industry, the gel formed after carbomer neutralization is an excellent matrix for preparing topical drugs (such as ointments, creams, and gels). It can effectively carry the active ingredients of the drug and promote its absorption through the skin. For example, topical preparations used for analgesia, anti-inflammatory, antifungal, treatment of acne or skin infections.
4. Liquid drug suspension stabilizer: Carbomer can effectively increase the viscosity of the water phase, prevent insoluble drug particles from settling and agglomerating in the suspension (such as oral suspension. Topical suspension), and ensure that each dose is accurate and uniform. This is common in children's medicines and certain antibiotic suspensions.
5. Emulsion stabilizer: In emulsion (oil-in-water type) cosmetics and medicines (such as creams, lotions), carbomer helps stabilize the dispersion of oil droplets by thickening the water phase, prevents oil-water separation (stratification or demulsification), and prolongs the shelf life of the product and improves spreadability.
6. Bioadhesive: Carbomer has bioadhesive properties, which means that it can adhere to the surface of moist biological tissues (such as skin, mucous membranes). This property is used to design drugs to prolong their local residence time (such as oral cavity, nasal cavity, eyes) and improve drug efficacy.
7. Cosmetic thickening and stabilization: Widely used in various cosmetic formulas:
Thickening essence, toner: Improve the use of products with strong fluidity,
Stabilize emulsification system: Such as sunscreen, moisturizer, BB cream, to prevent stratification.
Mask: As a thickening and molding matrix for gel or mud masks.
8. Toothpaste thickening and suspending agent: In toothpaste, carbomer plays two key roles:
Thickening: Give toothpaste appropriate paste consistency and extrudability. Suspension: Prevent abrasives (such as silica, calcium carbonate) and other insoluble ingredients from settling during storage and keep the paste uniform.
9. Mouthwash thickener: used to increase the viscosity of mouthwash, making it easier to retain and cover the surface in the mouth, improving the taste, and also helping to suspend insoluble ingredients (such as descaling agents, cooling agent particles)
10. Household cleaning products: used to thicken certain liquid detergents, disinfectants or fabric softeners to improve their spreadability and wall adhesion to achieve better cleaning or care effects.
Carbomer has been used in various pharmaceutical products for decades. It is completely allowed to be taken orally in the short or long term. It has no teratogenic, mutagenic or carcinogenic effects, and has no side effects on the skin and mucous membranes.
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