Polyquaternium-1 CAS 75345-27-6 Information
| CAS |
75345-27-6 |
| Molecular formula |
C33H70N5O6X2.5Cl |
| Molecular weight |
810.21 |
| EIENCS |
000-000-0 |
| Form |
White to light yellow flaky crystals or powder, or light yellow viscous liquid |
| Melting point |
84–86°C |
| boling point |
/ |
| Density |
/ |
| Solubility |
Readily soluble in DMSO, methanol (heated), and water (slightly dissolved); Slightly soluble in cold water (about 6 g/L) |
| PKA |
/ |
| Color |
White |
| Storage temp |
/ |
What is Polyquaternium-1 CAS 75345-27-6?
Polyquaternary ammonium salt-1 is a multifunctional cationic polymer. With its broad-spectrum antibacterial property, low irritation and good compatibility, it is widely used in the fields of medicine, personal care and industry. Its core value lies in:
Highly effective antiseptic: It replaces traditional preservatives (such as benzalkonium chloride) in ophthalmic preparations, offering higher safety.
Environmentally friendly: Biodegradable, suitable for water treatment systems;
Flexible process: Adjustable molecular weight (such as 36,000-40,000 Da), suitable for different formula requirements.
Polyquaternium-1 CAS 75345-27-6 Use
The field of medicine
Ophthalmic preparation preservatives: Widely used in contact lens care solutions and eye drops to inhibit microbial contamination (such as Pseudomonas and Staphylococcus aureus), with a concentration usually below 0.001%.
Drug intermediates: As raw materials for the synthesis of antiviral drugs and antidepressants (such as venlafaxine).
Personal care products
Preservative and conditioner: Used in shampoos, skin care products, wet wipes, etc., providing mild antibacterial and antistatic functions. Common concentrations are 0.001% - 0.1%.
Hair care products: Improve wet combing ability, luster and skin affinity of hair.
Industrial application
Water treatment: As a flocculant and biocide, it is used to treat oily wastewater or circulating cooling water systems (dosage: 20-200 mg/L).
Papermaking and textile: retention AIDS, antistatic agents and dye fixation agents.
Polyquaternium-1 CAS 75345-27-6 safety
Toxicity: Moderate toxicity: (Oral LD₅₀ in rats: 1550 mg/kg) Irritating to the skin and eyes (H315, H319)
Risk Identification: R36/38 (Irritation to eyes and skin), R43 (Skin sensitization)
Protective measures: Gloves and goggles must be worn during operation. Rinse immediately with water after contact with the skin
Storage conditions: Keep sealed, away from light, in a cool and well-ventilated place (<30℃); Keep away from oxidants and metals such as iron and copper
Shelf life: Approximately 2 years
