Potassium Tert-Butoxide CAS 865-47-4 Information
| CAS |
CAS 865-47-4 |
| Molecular formula |
C13H16N3NaO4S |
| Molecular weight |
333.33861 |
| EIENCS |
212-740-3 |
| Form |
Solution |
| Melting point |
256-258 °C (dec.) (lit.) |
| boling point |
275°C |
| Density |
0.910 g/mL at 20 °C |
| Solubility |
Soluble in hexane, toluene, diethyl ether and terahydrofuran. |
| PKA |
pK1:18(25°C) |
| Color |
White to off-white or slightly grayish |
| Storage temp |
|
What is Potassium Tert-Butoxide CAS 865-47-4?
Potassium tert-butanol, as a strong organic base catalyst, is widely used in the fields of medicine, pesticides and polymer synthesis due to its high reactivity. Key attention needed:
Operational safety: Strictly prevent moisture and fire, and wear complete protective equipment;
Process selection: Prioritize the use of environmentally friendly processes (such as the potassium hydroxide method) to reduce impurities;
Application adaptability: The liquid product (tert-butanol solution) has better stability and is suitable for industrial continuous reactions.
Potassium Tert-Butoxide CAS 865-47-4 Use
Organic synthesis catalyst
Condensation and rearrangement reactions: Catalytic Michael addition, Pinacol rearrangement, Ramberg-Backlund rearrangement, etc.
Alkylation reaction: Promotes the alkylation of the α -position of the carbonyl group, suitable for the bisalkylation of α,β -unsaturated ketones.
Darzens condensation: α -halogenated esters react with aldehydes/ketones to form epoxides.
Pharmaceutical and pesticide intermediates
A key base catalyst for the synthesis of antidepressants (such as venlafaxine) and pesticides (imidacloprid, cypermethrin).
Industrial application
Polymer materials: Curing agents for polyurethane and polyamide.
Electronics industry: Components of semiconductor cleaning agents and etching agents.
Potassium Tert-Butoxide CAS 865-47-4 safety
Flammability: Flash point 12.2° C. Flammable when exposed to open flame or high temperature. Stay away from heat sources.
Corrosiveness: Strongly corrosive to skin and eyes (H314); Protective gloves and goggles should be worn during operation
Reaction hazard: It releases intense heat and hydrogen gas when exposed to water. Avoid contact with damp environments
Storage conditions: Sealed, light-proof, nitrogen-protected, in a cool and dry place (<30℃)
