Salicylic acid CAS 69-72-7, Salicylic acid, CAS 69-72-7
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Salicylic acid (CAS 69-72-7), as a multifunctional organic acid, its core value lies in:Multi-scenario application: covering three major fields including medicine (aspirin raw materials), skin care (acne removal and exfoliation), and industry (rubber/dyes).
69-72-7
C7H6O3
138.12
200-712-3
| CAS | 69-72-7 |
| Molecular formula | C7H6O3 |
| Molecular weight | 138.12 |
| EIENCS | 200-712-3 |
| Form | Solid |
| Melting point | 158-161 °C(lit.) |
| boling point | 211 °C(lit.) |
| Density | 1.44 |
| Solubility | ethanol: 1 M at 20 °C, clear, colorless |
| PKA | 2.98(at 25℃) |
| Color | White to off-white |
| Storage temp | 2-8°C |
Salicylic acid (CAS 69-72-7), as a multifunctional organic acid, its core value lies in:
Multi-scenario application: covering three major fields including medicine (aspirin raw materials), skin care (acne removal and exfoliation), and industry (rubber/dyes);
Technological iteration: From alcohol-based solvent-based to 3D stereoscopic salicylic acid, with reduced irritation and sustained-release enhanced efficacy;
Safety boundary:
Cosmetics/food must strictly adhere to the upper limit of concentration (for long-lasting products, ≤2%; for preservative products, ≤0.5%).
Children's products must comply with the EU SCCS/1675/25 opinion;
Procurement suggestions: For industrial applications, choose 97% purity (¥8-12/kg), while for pharmaceuticals and cosmetics, 99%+ high purity grade is preferred.
Skin care products: (Acne removal/Exfoliation) 0.5-2%, gentle exfoliation, improves pore blockage, FDA and China National Medical Products Administration approved safe concentration.
Skin disease treatment preparations: 3-10%, for treating tinea, psoriasis, and chapping of hands and feet (under the guidance of a doctor).
Chemical peels: 30% fade pigmentation and fine lines (professional operation required).
Preservative: ≤0.5% (food/cosmetics), inhibits microorganisms and extends shelf life.
Rubber industry: Anti-scorching agent, ultraviolet absorber;
Electroplating/dyes: Metal ion color developers (titanium, zirconium), complexing agents;
Spice synthesis: Preparation of methyl salicylate, ethyl salicylate, etc.
Toxicity and irritation
Acute toxicity: Oral LD₅₀ >500 mg/kg in rats (low toxicity), but corrosive to the skin and mucous membranes;
Eye irritation: Contact with the eyes may cause serious damage.
2. Regulatory restrictions (Latest assessment by the European Union)
Children's products (3-10 years old) :
❌ Prohibited use scenarios: containing 3% rinsing hair products, containing 2% retention products (non-body lotion), containing 0.5% body lotion;
✔️ Safety scenario: Preservative use (0.5%) Use alone in body lotion, skin care and oral products.
Pregnant women/lactating period: Avoid high concentrations of CMR category 2 reproductive toxic substances.
3. Chinese standards
Cosmetics: Concentration limit 2%;
Food additives: They must comply with the limits stipulated in the "National Food Safety Standard" (e.g., for baked goods, ≤55mg/kg).
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