Sodium Dichloroacetate CAS 2156-56-1, Sodium Dichloroacetate, CAS 2156-56-1
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Sodium dichloroacetate, as a PDK-targeted inhibitor, has significant potential in the treatment of metabolic diseases and cancer, but the risk of neurotoxicity needs to be strictly managed.
2156-56-1
C₂HCl₂NaO₂
150.92
218-461-3
| CAS | 2156-56-1 |
| Molecular formula | C₂HCl₂NaO₂ |
| Molecular weight | 150.92 |
| EIENCS | 218-461-3 |
| Form | White to slightly yellowish crystalline powder with strong hygroscopicity |
| Melting point | 189–199°C |
| boling point | / |
| Density | / |
| Solubility | |
| PKA | |
| Color | White |
| Storage temp |
Sodium dichloroacetate, as a PDK-targeted inhibitor, has significant potential in the treatment of metabolic diseases and cancer, but the risk of neurotoxicity needs to be strictly managed. Industrial-grade products are widely used in the synthesis of flame-retardant materials, while pharmaceutical-grade products need to pay attention to purity and storage stability. When making a purchase, it is recommended to select the purity (≥99%, pharmaceutical grade preferred) based on the intended use and abide by the safety operation norms
Organic synthesis: Used as intermediates for pesticides and dyes as well as precursors of carboxylate salts.
Flame retardants: Added to materials such as epoxy resins and polycarbonate to enhance self-extinguishing properties.
Research tools: Laboratory reagents for regulating cell metabolism.
Hazard Indication: Xi (Irritating), Xn (Harmful)
Risk terms: R36/37/38 (Irritation to eyes/respiratory tract/skin), R40 (potential carcinogenicity)
Protective measures: Wear gloves and goggles; Avoid inhaling dust
Storage conditions: Keep sealed and away from light, and store in an inert atmosphere at 2-8 ℃. Stay away from strong acids/oxidants
Toxicity data: Oral LD₅₀ in rats =5281 mg/kg; Long-term high doses cause neuropathy
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