Vitamin A1 Retinol CAS 68-26-8, Vitamin A1 Retinol, CAS 68-26-8
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Vitamin A₁ (retinol, CAS 68-26-8) is an essential nutrient and irreplaceable in the fields of vision, immunity and anti-aging.
68-26-8
C₂₀H₃₀O
286.452
200-683-7
| CAS | 68-26-8 |
| Molecular formula | C₂₀H₃₀O |
| Molecular weight | 286.452 |
| EIENCS | 200-683-7 |
| Form | Yellow to orange crystalline solid or pale yellow oily liquid |
| Melting point | 61-63℃ (retinol) 17-19℃ (Vitamin A₂) |
| boling point | 137-138℃ (decomposition) |
| Density | 0.9933 (rough estimate) |
| Solubility | Insoluble in water and glycerol; It is readily soluble in ethanol, chloroform and oils |
| PKA | 14.09±0.10(Predicted) |
| Color | Yellow to orange |
| Storage temp | -20°C |
Vitamin A₁ (retinol, CAS 68-26-8) is an essential nutrient and irreplaceable in the fields of vision, immunity and anti-aging. Its application requires a balance between activity and stability (esterification form is preferred), and strictly adheres to the addition limits in food/cosmetics to avoid toxicity risks. Researchers and industrial developers should focus on the transformation efficiency and bioavailability optimization of their derivatives.
Feed additives: To prevent vitamin A deficiency in livestock and poultry, retinol acetate (with higher stability) is commonly used.
Anti-aging skin care products
Derivatives: Retinol palmitate, retinol acetate, hydroxypinazone retinate (HPR).
Functions: Promote epidermal thickening and collagen regeneration (effective within 24 weeks at 0.4% concentration).
Safety limits: Norway stipulates that retinol ≤0.3% and retinol palmitate ≤0.7%.
Medicine: For the treatment of night blindness, dry eyes, and complications of measles (under the guidance of a doctor to avoid overdose and poisoning).
Toxicity: Excessive intake (> 100,000 IU/ day) may cause headache, liver damage and decreased bone density.
Stability measures: It should be stored away from light and at low temperatures. The product often enhances its antioxidant properties in the form of acetate/palmitate.
Regulation example:
Taiwan: Capsules/tablets are limited to 10,000 IU (3,000 μg RE) per day.
The European Union (SCCS) : Recognizes the safety of retinol and its esters in cosmetics.
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