"Methyl niacin appears in the form of crystals or crystalline powder ranging from white to brown in appearance. When people observe carefully, they will find that it has a unique odor characteristic, which is a mixture of fresh scent, caramel-like sweetness, the rich flavor of nuts and a slight tobacco smell."
-Deshangchemical
Methyl niacin appears in the form of crystals or crystalline powder ranging from white to brown in appearance. When people observe carefully, they will find that it has a unique odor characteristic, which is a mixture of fresh scent, caramel-like sweetness, the rich flavor of nuts and a slight tobacco smell. This complex and unique odor makes it have a certain degree of recognition among many chemical substances.
Methyl nicotinate is an irritating substance to human skin. When it comes into contact with human skin, it may cause uncomfortable reactions on the skin. Not only that, it also has a significant dilating effect on blood vessels, enabling them to expand to a certain extent.
In terms of practical application, the main purpose of methyl nicotinate is to be used as a "red additive". When applied to the skin, it will cause redness, swelling or inflammation in the skin within a short period of time. Based on this characteristic, it is often used in lip augmentation or other lip products. Among these products, methyl niacin can achieve the effect of lip augmentation by causing a redness and swelling reaction on the lips, making them look fuller and rosier.
In addition to its application in beauty products, methyl nicotinate is also an active ingredient in many veterinary preparations. In the field of veterinary medicine, it is mainly used for local application and plays the role of a red additive. For example, when treating various animal diseases, it can have positive effects on different conditions. For respiratory system diseases, methyl nicotinate can improve local blood circulation through its vasodilatory effect, which is helpful in alleviating inflammation and discomfort in the respiratory tract. For vascular diseases such as edema and hematoma, it can help relieve the congestion and swelling of blood vessels, promote the absorption of blood and the recovery of circulation. At the same time, when treating rheumatoid diseases in cattle and horses, nicotinate methyl ester can also play a certain role. By improving local blood circulation and metabolism, it can relieve joint pain and inflammation. It should be noted that the concentration of the veterinary drug preparation involved here is 2%, but there are no detailed explanations on other aspects at present.
From the perspective of chemical synthesis, methyl nicotinate is prepared through the esterification reaction of nicotinic acid with methanol in the presence of concentrated sulfuric acid. After the esterification reaction is completed, 10% sodium bicarbonate is used for neutralization treatment to neutralize the remaining acidic substances in the reaction system. Subsequently, through the extraction method, methyl nicotinate was extracted into the organic solvent chloroform, thereby obtaining a relatively pure methyl nicotinate product.
In addition, regarding the research on the DOI synthesis and analgesic activity of methyl nicotinate, the relevant information can be further consulted and understood in the literature "10.4314/ jbp.v12i1.8".
