choline glycerophosphate CAS 28319-77-9 alpha GPC, choline glycerophosphate, CAS 28319-77-9 alpha GPC
Alpha-GPC (L-α-Glycerophosphorylcholine, CAS28319-77-9) is a highly pure, highly hydrophilic phospholipid derivative that can quickly deliver choline to the brain.
28319-77-9
C8H20NO6P
257.22
248-962-2
CAS | 28319-77-9 |
Molecular formula | C8H20NO6P |
Molecular weight | 257.22 |
EIENCS | 248-962-2 |
Form | solid |
Melting point | 142.5-143° |
boling point | / |
Density | / |
Solubility | Very high water solubility, about 1000 g/L (25°C) |
PKA | / |
Color | white |
Storage temp | -20°C |
Alpha-GPC (L-α-Glycerophosphorylcholine, CAS28319-77-9) is a highly pure, highly hydrophilic phospholipid derivative that can quickly deliver choline to the brain. It is widely used in research and cognitive improvement supplements, but it is recommended to adhere to GRAS recommended doses and pay attention to cardiovascular safety data.
Biochemical research:
Used for phospholipid and acetylcholine pathway research and cell membrane synthesis experiments
Used for alleviating choline-dependent defect and other cell models
Dietary supplements/medicines:
Increase the availability of choline in brain tissue, as an acetylcholine precursor, which helps enhance memory and cognition
Used for improving cognitive impairment and brain function in the elderly (such as Alzheimer's disease, vascular dementia)
Drug status: OTC products in most countries
GRAS (US FDA): The upper limit of daily intake is 196.2 mg, which is considered "generally recognized as safe"
Potential risks: Samsung's TMAO metabolites may increase cardiovascular risk; some cohort studies reported that the risk of stroke in users increased by nearly 46%, but subsequent analysis believed that there were confounding factors
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