What is Crospovidone CAS 25249-54-1?
Cross-linked polyvinylpyrrolidone (PVPP) can be regarded as a polymer formed by the physical or chemical cross-linking of linear PVP molecular chains. The PVPP obtained through different synthesis methods varies in some properties due to the different cross-linking methods and degrees of cross-linking. Depending on the degree of cross-linking, PVPP exhibits super water-absorbing resin (low cross-linking degree), water-absorbing gel (medium cross-linking degree), and insoluble substances (high cross-linking degree). Compared with PVP, PVP is a water-soluble polymer, while PVPP can only swell in water.
Crospovidone CAS 25249-54-1 Use
Cross-linked polyvinylpyrrolidone (PVPP) is a kind of insoluble polymer in water, strong acids, strong bases and common organic solvents, which is formed by the polymerization of vinylpyrrolidone monomer under specific conditions. As an important high-molecular fine chemical product, PVPP has many excellent and unique properties and has been widely applied in cosmetics, food, medicine and other fields.
Used in the beverage and pharmaceutical industries
Due to the high molecular weight and cross-linked structure of cross-linked polyvinylpyrrolidone, it is insoluble in water but can rapidly cause the network structure to expand and produce disintegration effect when exposed to water. In the field of medicine, cross-linked polyvinylpyrrolidone (Chemicalbook) pyrrolidone is widely used as a disintegrant for tablets, and is also widely used as a suspension stabilizer, a drug component complexing agent, and a complexing agent for tannins and polyphenols in plant-based drugs.
Cross-linked polyvinylpyrrolidone (PVP-P) can form complexes with phenols and alkaloids, thereby removing them from plant samples. This prevents the modification and interference of proteins in eggs, allowing for more accurate determination of protein content. There are also reports indicating that cross-linked polyvinylpyrrolidone (PVP-P) can enhance the activity of enzymes.
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