2-hydroxypropyl-beta-cyclodextrin CAS 128446-35-5 HPCD,2-hydroxypropyl-beta-cyclodextrin, CAS 128446-35-5 HPCD
As a broad-spectrum chelating agent and formulation stabilizer, sodium edetate (CAS 64-02-8) is leading various industries to move steadily towards green, efficient and safe directions with its excellent performance, safety and reliability, and multi-field adaptability.
128446-35-5
C63H112O42
1541.54
420-920-1
| CAS | 128446-35-5 |
| Molecular formula | C63H112O42 |
| Molecular weight | 1541.54 |
| EIENCS | 420-920-1 |
| Form | solution (clear, colorless) |
| Melting point | [α]26/D +139°, c = 1 in H2O |
| boling point | Soluble in water. |
| Density | / |
| Solubility | H2O: 45 % (w/v) |
| PKA | / |
| Color | White to slightly yellow |
| Storage temp | room temp |
As a broad-spectrum chelating agent and formulation stabilizer, sodium edetate (CAS 64-02-8) is leading various industries to move steadily towards green, efficient and safe directions with its excellent performance, safety and reliability, and multi-field adaptability. In the future formulation design that emphasizes functionality and environmental compatibility, sodium edetate is undoubtedly a key raw material worthy of in-depth development.
1.Metal chelators and stabilizers in the pharmaceutical industry
In pharmaceutical preparations, sodium edetate CAS 64-02-8 is widely used as a chelating agent and antioxidant stabilizer for drug formulations. It prevents active ingredients from being degraded due to metal catalysis by chelating trace metal ions, prolongs the shelf life of drugs, and ensures the consistency of ingredient activity. It is commonly found in injections, eye drops, oral solutions, antibiotic preparations, etc.
In addition, EDTA disodium can also be used to treat certain heavy metal poisoning (such as lead, mercury, etc.), and assists in the excretion of metals in the body by forming soluble complexes, which plays an important role in the field of medical toxicology.
2.Formula stabilizer in cosmetics and daily chemical products
In the cosmetics and personal care industry, sodium edetate is an indispensable functional additive, widely used in cleansers, lotions, emulsions, essences, sunscreens, shampoos, conditioners and other products. Its core functions are:
Chelate metal ions in water to prevent discoloration, precipitation or oxidation of the formula;
Stabilize the emulsification system and extend the shelf life of the product;
Increase the activity of preservatives, reduce the concentration of use, and enhance the mildness of the formula.
Its mild and hypoallergenic properties make it particularly suitable for sensitive skin or infant care products.
3.Metal control and antioxidants in the food industry
In the food industry, disodium EDTA (CAS 64-02-8) is often used as an antioxidant synergist or metal ion controller to delay food oxidation and deterioration. Its typical applications include:
Dairy products, sauces, canned foods, salad dressings, etc.;
Inhibit metal-induced rancidity in oil products;
Use in combination with vitamin C, ascorbyl palmitate, etc. to improve overall antioxidant capacity.
It should be emphasized that the use of sodium edetate in food must comply with the food additive regulations and standards of various countries, such as China's "GB 2760", the US FDA GRAS list, and the EU EFSA license range.
4.Industrial water treatment and metal cleaning fields
Sodium edetate CAS 64-02-8 is often used as a water softener, metal ion scavenger and complexing agent in industrial applications. Its typical scenarios include:
Hard water treatment and descaling of industrial boilers, condensers, and air conditioning systems;
Metal surface degreasing, rust removal and electroplating pretreatment;
Used in detergents and detergents in conjunction with surfactants to improve decontamination efficiency.
Its good complexing ability can effectively improve equipment operating efficiency, reduce sediment formation, and extend equipment life.
5.Agricultural trace element carrier and foliar fertilizer additive
In modern agriculture, EDTA disodium is used as a chelating agent for trace metal elements (such as Fe, Zn, Mn, Cu, etc.) to prevent metal precipitation and improve nutrient absorption efficiency. It is widely used in:
Foliar fertilizer, root nutrient solution formulation;
Element balance in facility agriculture (such as hydroponic systems);
Metal activation treatment in soil conditioners.
Globally, sodium edetate CAS 64-02-8 has been certified as a safe additive by multiple authoritative organizations:
Listed on the GRAS (Generally Recognized As Safe) list by the U.S. FDA;
Approved for use in cosmetics by EU Regulation EC 1223/2009;
Complies with the relevant provisions of China's national standard "GB 2760" on food additives.
Nevertheless, long-term high-dose intake of sodium edetate still requires caution, especially patients with renal insufficiency should avoid intake. In industrial and agricultural applications, emissions must also be strictly controlled to avoid metal migration or ecological interference in the environment.
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