lithium aluminum hydride CAS 16853-85-3 LAH,lithium aluminum hydride,CAS 16853-85-3 LAH
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Lithium Aluminum Hydride (LAH, CAS 16853-85-3) is a powerful reducing agent widely used in pharmaceuticals, fine chemicals, and organic synthesis, requiring strict moisture-free handling for safety.
16853-85-3
LiAlH4
37.954298
240-877-9
| CAS | 16853-85-3 |
| Molecular formula | LiAlH4 |
| Molecular weight | 37.954298 |
| EIENCS | 240-877-9 |
| Form | tablets (~0.5 g each) |
| Melting point | 125 °C (dec.)(lit.) |
| boling point | 0°C |
| Density | 0.97 g/mL at 20 °C |
| Solubility | Reacts |
| PKA | / |
| Color | White to light gray |
| Storage temp | Store below +30°C. |
Lithium Aluminum Hydride (LAH, CAS 16853-85-3) is a commonly used strong reducing agent. It is a white or off-white crystalline powder with extremely high chemical activity. It is widely used in the fields of pharmaceuticals, fine chemicals and organic synthesis, and can effectively reduce a variety of organic functional groups to alcohols or amines. Because it reacts violently with water and releases hydrogen, LAH must be used and stored under strictly controlled environmental conditions to ensure safe operation.
1. Organic synthesis:
It is a powerful reducing agent used to reduce esters, acids, nitriles, amides, aldehydes, ketones and other compounds to alcohols or amines.
It is used as a key reducing agent in pharmaceuticals, fine chemicals and agricultural chemicals.
2. Pharmaceutical industry:
It is used for the transformation of difficult-to-reduce functional groups in the synthesis of active pharmaceutical ingredients (API).
3. Fine chemicals and materials:
It plays an important role in fragrances, dyes, specialty chemicals and material modification.
Strong reducing property and danger: Lithium Aluminum Hydride (LAH) will decompose rapidly when in contact with water, releasing a large amount of flammable hydrogen, which may cause fire or explosion. Therefore, contact with water, moisture and acidic substances must be strictly avoided during operation.
Protective measures: The operation must be carried out in an anhydrous environment and under the protection of inert gas (such as nitrogen, argon). Protective glasses, chemical-resistant gloves and protective clothing should be worn, and special anhydrous solvents (such as ethers) should be used.
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