nuciferine CAS 475-83-2, nuciferine, CAS 475-83-2
In the rich and colorful plant world, lotus leaf alkaloid, as a unique substance, has its specific source and remarkable characteristics. Lotus leaf alkaloid is a kind of afenine-type alkaloid carefully extracted from the dried fallen leaves of the lotus plant of the Nymphaeaceae family.
475-83-2
C19H21NO2
295.38
618-170-5
Chemical Name | Nuciferine |
Other Name | Dapoxetine; (-)-nucipherine; (r)-1,2-dimethoxyaporphine |
CAS | 475-83-2 |
EINECS | 618-170-5 |
Type | Plant extracts; Pharmaceutical, pesticide and dye intermediates |
Molecular Formula | C19H21NO2 |
Molecular Weight | 295.38 |
Melting point | 165.5°C |
Boiling point | 437.06°C (rough estimate) |
density | 1.1156 (rough estimate) |
refractive index | 1.5000 (estimate) |
storage temp. | 2-8°C |
solubility | DMSO : 11.11 mg/mL (37.61 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) |
form | powder |
In the rich and colorful plant world, lotus leaf alkaloid, as a unique substance, has its specific source and remarkable characteristics. Lotus leaf alkaloid is a kind of afenine-type alkaloid carefully extracted from the dried fallen leaves of the lotus plant of the Nymphaeaceae family. In the vast lotus pond, those seemingly ordinary lotus leaves, after going through a series of scientific and rigorous extraction processes, can bring us this alkaloid of great value.
Lotus leaf alkaloid plays a crucial role in lotus leaves and is the main lipid-lowering active component in them. To effectively obtain lotus leaf alkaloid from dried and crushed lotus leaves, researchers have explored and employed a variety of advanced methods. Among them, cellulase pretreatment is a crucial preliminary step. Through this treatment method, the cellulose structure in lotus leaves can be moderately adjusted and optimized, creating more favorable conditions for the subsequent extraction of alkaloids from lotus leaves.
In the process of removing impurities, the hydrochloric acid dilution removal method plays an important role. This method can precisely target some specific impurity components in lotus leaves. By taking advantage of the chemical properties of hydrochloric acid, under appropriate concentration and conditions, the impurities are gradually decomposed and removed, thereby enhancing the purity of the alkali in lotus leaves.
Ultrasonic-assisted removal is also one of the commonly used methods. The unique wave characteristics of ultrasonic waves can have an effect on various components in lotus leaves at the microscopic level. It can cause subtle changes in the cellular structure of lotus leaves, promote better separation of impurities from lotus leaf alkaloids, and further enhance the extraction efficiency and purity.
And the chloroform removal method is equally indispensable. Chloroform, as an organic solvent, has specific solubility and can selectively dissolve and remove certain specific impurities in lotus leaves, enabling lotus leaf alkaloid to be extracted more purer.
In the treasure house of traditional Chinese medicine, lotus leaves hold a unique position and value. According to the theoretical system of traditional Chinese medicine, lotus leaves are bitter and neutral in nature, and they belong to the liver, spleen, stomach and heart meridians. This unique nature, taste and meridian tropism characteristics determine its significant role in the regulation of human health. Lotus leaves have the effect of clearing heat and dampness, just like a silent guardian of coolness, which can help the human body dispel the evil of damp heat and keep the internal environment of the body fresh and balanced.
Qingyang is also one of the important benefits of lotus leaves. It is like a warm ray of sunlight, capable of stimulating the body's Yang energy, promoting the smooth flow of qi and blood, and enabling the body's physiological functions to operate normally. Meanwhile, lotus leaves also have the magical effect of cooling the blood and stopping bleeding. For some bleeding symptoms caused by excessive blood heat, lotus leaves can exert their unique pharmacological effects, helping to stop bleeding and cool the blood, and maintaining the health of the human blood.
The main components of lotus leaves, apart from lotus leaf alkaloid, also include citric acid, oxalic acid, etc. These components work together to form the rich and unique chemical system of lotus leaves. Among them, lotus leaf alkaloid plays a major role in the fat-burning process, just like a key to ignite the fire of fat metabolism, capable of activating the fat breakdown and consumption mechanism within the human body.
The practical achievements of medical research have also fully demonstrated the many magical effects of lotus leaves. Studies show that lotus leaves have diuretic and laxative effects. They act like gentle intestinal cleaners, promoting intestinal peristalsis in the human body, increasing the frequency of defecation, helping the human body eliminate toxins and waste from the body, and keeping the intestines clean and healthy.
In addition, lotus leaves can also eliminate toxins in the digestive tract. It seems like a meticulous guardian, capable of penetrating deep into the human digestive tract, eliminating all kinds of toxins hidden within one by one, and creating a clean and healthy environment for the human digestive system.
In terms of lowering lipid and removing oil, lotus leaves perform exceptionally well. It is like an efficient grease cleaner, capable of effectively breaking down and metabolizing the excess fat inside the human body, reducing the accumulation of fat in the body, and helping people maintain an ideal weight and figure.
Clearing heat and relieving summer heat is also an important function of lotus leaves. On a hot summer day, lotus leaves can bring a touch of coolness to the human body, relieve the discomfort caused by high temperatures, and make people feel refreshed and comfortable.
More importantly, lotus leaves can significantly reduce the levels of triglycerides and cholesterol in the serum. This function is of great significance for the management of blood lipids in the human body. Just like a precise blood lipid regulator, it can keep the blood lipid levels in the human body within a reasonable range and prevent and improve the risk of various cardiovascular diseases.
It is precisely because lotus leaves have so many health benefits that using lotus to represent weight loss does not require calculation for weight loss and has no adverse effects on the human body. It helps people achieve the goals of healthy weight loss and physical conditioning in a natural and gentle way, and has become an ideal choice for people in their pursuit of a healthy life.
The following is the expanded content:
** Application aspect ** :
This substance has important applications in many scientific research and professional fields, especially suitable for content determination. In rigorous drug research and development, component analysis and other work, through precise content determination, the specific content of the substance in a particular sample can be accurately known, providing key data support for subsequent research and quality control. At the same time, it is also often used in identification work. With the help of professional technical means and instruments and equipment, based on its unique chemical properties, physical characteristics, etc., it can accurately identify the authenticity and category of the substances used in relevant research and application scenarios, ensuring that the substances used in related research and application scenarios are accurate and reliable. In addition, it also plays an indispensable role in pharmacological experiments, providing important experimental materials and research objects for in-depth study of the interaction between drugs and the body, exploration of the mechanism of action and potential therapeutic effects of drugs, etc.
** Pharmacological effects ** :
After extensive scientific research and experimental verification, it was found that this substance has a significant effect on weight loss and fat reduction. During the process of human metabolism, it can ingeniously regulate the metabolic pathways of fat, promote the decomposition and consumption of fat, and reduce abnormal accumulation of fat in the body. Specifically, it can act on fat cells, activate related fat-decomposing enzymes, and promote the gradual breakdown of fat components such as triglycerides into smaller molecules, which are then excreted from the body through normal metabolic pathways. At the same time, it can also rationally regulate the energy metabolism of the body, inhibit excessive calories from being converted into fat and stored, thereby helping people achieve the goals of weight loss and fat reduction, and has shown a good application prospect in the field of prevention and treatment related to obesity.
** Efficacy ** :
This substance has the effect of clearing heat and relieving summer heat. In a hot environment, the human body is prone to discomfort symptoms such as dry heat and fatigue. However, it can effectively eliminate the heat pathogen generated in the body due to high temperature, regulate the body's temperature balance, make people feel refreshing and comfortable, as if bringing a cool breeze to the body and alleviating the discomfort caused by summer heat. Moreover, it also helps promote the development of clear Yang. In traditional Chinese medicine theory, clear Yang is crucial for maintaining the normal physiological functions of the human body. It can facilitate the normal ascent and circulation of clear Yang within the body, making the flow of qi and blood in the body smoother, enabling better coordination and exertion of the functions of various internal organs, and enhancing the overall vitality and resistance of the body.
In addition, cooling the blood and stopping bleeding is also one of the important functions of this substance. When the human body experiences conditions such as blood heat flowing wildly, blood may overflow outside the pulse, leading to various bleeding symptoms. This substance can exert its effect of cooling the blood, eliminating the heat pathogen in the blood and restoring the normal circulation state of the blood, thereby achieving the purpose of stopping bleeding. It has certain application value in the treatment and conditioning of some hemorrhagic diseases caused by blood heat.