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Sodium Edetate (EDTA Disodium Salt, CAS 64-02-8) is a common chelating agent, widely used in industry, medicine, cosmetics and food additives.
64-02-8
C10H12N2Na4O8
380.17
200-573-9
| CAS | 64-02-8 |
| Molecular formula | C10H12N2Na4O8 |
| Molecular weight | 380.17 |
| EIENCS | 200-573-9 |
| Form | Crystalline Powder |
| Melting point | >300 °C(lit.) |
| boling point | / |
| Density | Apparent density: 6.9 lb/gallon |
| Solubility | H2O: 0.1 g/mL, clear, colorless |
| PKA | / |
| Color | White |
| Storage temp | / |
Sodium Edetate (EDTA Disodium Salt, CAS 64-02-8) is a common chelating agent, widely used in industry, medicine, cosmetics and food additives. It can effectively inhibit the catalytic reaction of metal ions and prevent product deterioration, oxidation or precipitation by forming a stable complex with metal ions (such as Ca²⁺, Mg²⁺, Fe³⁺, etc.).
Medicine and injection
Used as calcium/magnesium antagonist to treat hypercalcemia or heavy metal poisoning
Control of metal ions in water for injection and dialysate
Cosmetics and daily chemical products
Used as preservative stabilizer to delay lipid oxidation
Widely used in facial cleansers, shampoos, lotions, and creams to improve formula stability
Food industry (when it meets food grade standards)
Inhibit discoloration and oxidation caused by metal ions
Used for quality protection of canned food, beverages, dairy products, etc.
Water treatment
As a water softener and complexing agent to prevent boiler scaling and scale formation
Used for metal ion stabilization control in circulating water systems and cooling towers
Industrial applications
Printing and dyeing auxiliaries, paper bleaching stabilizers
Metal cleaning agents, complexing agents, and electroplating solution formulation ingredients
Sodium Edetate (Disodium EDTA) is a chemical raw material that has been widely used for decades and has a good safety record. It is considered to have little impact on the human body and the environment, especially under appropriate dosage and control. Its safety has been recognized by multiple international regulatory agencies, including:
FDA (U.S. Food and Drug Administration): approved as a pharmaceutical excipient and food additive (limited use)
EU REACH Regulation: registered and allowed to be used in multiple industries
Cosmetic Ingredient Review (CIR) Expert Group: confirmed that its use in personal care products is safe (concentrations usually do not exceed 0.1%–2%)
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