"A practical supplier guide to 4'-methylpropiophenone (CAS 5337-93-9): what the ketone is, its synonyms and spec sheet (C10H12O, MW 148.2, EINECS 226-267-5), where it is used as an agrochemical, fragrance, and organic building-block intermediate, plus handling, packaging, and sourcing notes."

-Deshangchemical-chemechemi

What 4'-Methylpropiophenone Actually Is

4'-Methylpropiophenone, listed under CAS 5337-93-9, is an aromatic ketone that most buyers know by one of its longer names: p-tolyl ethyl ketone, 4-propionyltoluene, or simply ethyl p-tolyl ketone. The IUPAC form is 1-(4-methylphenyl)-1-propanone. On paper the numbers are small and easy to remember: molecular formula C10H12O, molecular weight 148.2 g/mol, EINECS 226-267-5. Supplied by chemechemi it ships as a high-purity liquid, which is why it moves comfortably through standard drum and bottle handling without the caking and lumping problems you get with solid fine-chemical intermediates.

Customers who have only seen the Chinese or catalogue short form sometimes type "p-methylpropiophenone" or "4-methylpropiophenone" into a search box. They all point to the same material. If you are matching a bill of materials or a synthesis route, the CAS number is the only field that removes doubt, so we always confirm CAS 5337-93-9 before a first commercial quote.

Where It Fits in a Synthesis Chain

This ketone is a classic organic building block. The propionyl group hanging off the para-methylated benzene ring is reactive enough to be carried into longer molecules, and the methyl on the ring is a convenient handle for downstream substitution. In practice that makes 4'-methylpropiophenone a recurring starting point in three areas.

First, agrochemical intermediates. Aromatic ketones of this shape are routinely condensed, reduced, or cyclised into the active cores of crop-protection molecules. Buyers in this segment usually care most about consistent assay and low residual solvent, because a few tenths of a percent of impurity can throw off a multi-step pilot run.

Second, fragrance and perfume ingredients. The p-tolyl ethyl ketone skeleton shows up as a structural fragment in aroma-chemical synthesis, where a clean, pale liquid with stable odor profile matters more than absolute grade. Perfume houses tend to request smaller, tighter-packed lots and tighter metal-impurity limits.

Third, general organic intermediate work. Laboratories and toll manufacturers use it as a ketone partner in Grignard, aldol, and reductive-amination routes. For these customers the appeal is availability: chemechemi keeps it in a 1 kg minimum order with free samples on request, so a bench chemist can validate a route before committing to a drum.

Key Specifications Buyers Should Verify

Before you place an order, check the points below against your own specification sheet. We list our standard values so the conversation starts from the same place.

Handling, Storage, and Packaging

As a liquid aromatic ketone, 4'-methylpropiophenone is stable under normal warehouse conditions but should be kept in a sealed container away from strong oxidisers and direct sunlight. We ship in standard chemical packaging and can arrange custom repacking or blending at our facility, which is useful if your downstream step needs a specific drum size or a pre-weighed intermediate. Because the material is a refined liquid, drum liners and tight caps matter more than desiccants; the main risk in storage is slow pickup of moisture at the thread, which a good seal prevents.

For sampling and small R&D orders, the 1 kg MOQ plus free-sample policy means you can run a full set of in-house tests, GC, and residual-solvent work before scaling. For production volumes, plan around the 7-15 day delivery window and confirm Incoterms (we handle FOB, CIF, EXW, and express) at the quoting stage so freight and insurance are not a surprise.

Related Ketones and Building Blocks

4'-Methylpropiophenone rarely travels alone in a formulation pipeline. Procurement teams often source its ethyl homolog and the parent ketone in the same package. The 4'-ethylpropiophenone (CAS 27465-51-6) is the natural next member of the same series, and acetophenone (CAS 98-86-2) is the parent ketone many routes branch from. If your route introduces an amine or a protecting group downstream, the N-ethylmethylamine (CAS 624-78-2) and Boc anhydride (CAS 24424-99-5) we stock sit on the same bill of materials. For halogenation steps, 2-bromoacetophenone (CAS 536-38-9) is another ketone intermediate worth keeping on the same supplier list.

Why Buy From chemechemi

Shandong Deshang Chemical, the manufacturer behind chemechemi, has run foreign-trade operations since 2002 and exports to more than 140 countries. The practical benefits for a buyer are concrete: a single source for mixed intermediate orders, in-house QC with pre-shipment reports, third-party inspection on request, and a warehouse that can hold and repack imported goods. For 4'-methylpropiophenone specifically, the combination of 1 kg MOQ, free samples, and 1,000 tons/year capacity means the same supplier works for both a bench-scale validation and a full commercial campaign.

If your team is scouting a ketone intermediate for an agrochemical, fragrance, or pharmaceutical building-block project, start from the 4'-methylpropiophenone (CAS 5337-93-9) product page to pull the current specification sheet, request a sample, and confirm lead time. Matching CAS 5337-93-9 on both sides of the quote is the fastest way to avoid a mislabeled intermediate derailing a multi-step synthesis.