"A practical supplier guide to 4'-ethylpropiophenone (CAS 27465-51-6): what the ketone is, its synonyms and spec sheet (C11H14O, MW 162.2, EINECS 2017-001-1), where it is used as an agrochemical, pharmaceutical, and specialty organic building-block intermediate, plus handling, packaging, and sourcing notes."
-Deshangchemical-chemechemi
What 4'-Ethylpropiophenone Actually Is
4'-Ethylpropiophenone, registered under CAS 27465-51-6, is an aromatic ketone that sits one carbon above its well-known methyl cousin in the same intermediate family. Buyers usually meet it under a handful of equivalent names: p-ethylpropiophenone, 4-ethylpropiophenone, ethyl p-ethylphenyl ketone, or the IUPAC form 1-(4-ethylphenyl)-1-propanone. The numbers on the specification sheet are small and stable: molecular formula C11H14O, molecular weight 162.2 g/mol, EINECS 2017-001-1. At chemechemi it is supplied as a refined, high-purity liquid, which is the main reason it moves through ordinary drum and bottle handling without the caking problems you see with solid fine-chemical intermediates.
Procurement staff who only know the short form sometimes search for "ethylpropiophenone" or "p-ethylpropiophenone." Both resolve to the same material. When you are matching a bill of materials or a multi-step synthesis route, the CAS number is the only field that settles the matter, so we always confirm CAS 27465-51-6 before issuing a first commercial quote.
Where It Fits in a Synthesis Chain
This ketone is a straightforward organic building block. The propionyl group attached to the para-ethylated benzene ring is reactive enough to be carried into longer molecules, and the ethyl substituent on the ring is a useful handle for downstream substitution or further alkylation. In day-to-day sourcing it shows up most often in three places.
First, agrochemical intermediates. Aromatic ketones of this shape are routinely condensed, reduced, or cyclised into the active cores of crop-protection molecules. Buyers in this segment care most about a consistent assay and low residual solvent, because a few tenths of a percent of impurity can throw off an entire pilot campaign.
Second, specialty organic synthesis and pharmaceutical building blocks. The extra ethyl group gives formulators a slightly more lipophilic ketone than the methyl analogue, which matters when a route needs a specific logP profile in the intermediate. Laboratories and toll manufacturers use it as a ketone partner in Grignard, aldol, and reductive-amination sequences.
Third, general fine-chemical production. Because chemechemi keeps it at a 1 kg minimum order with free samples on request, a bench chemist can validate a route before committing to a full drum, and a production planner can later scale the same material without changing suppliers.
Key Specifications Buyers Should Verify
Before placing an order, check the points below against your own specification sheet. We list our standard values so the conversation starts from the same baseline.
| Item | Typical Value |
|---|---|
| CAS number | 27465-51-6 |
| Synonyms | p-Ethylpropiophenone; 4-ethylpropiophenone; ethyl p-ethylphenyl ketone; 1-(4-ethylphenyl)-1-propanone |
| Molecular formula | C11H14O |
| Molecular weight | 162.2 g/mol |
| EINECS | 2017-001-1 |
| Appearance | High-purity refined liquid |
| Grade | Refined, intermediate / synthesis use |
| MOQ | 1 kg (free sample available, shipping at buyer cost) |
| Production capacity | 1,000 tons / year |
| Lead time | 7-15 days |
| Origin | Shandong, China |
Handling, Storage, and Packaging
As a liquid aromatic ketone, 4'-ethylpropiophenone is stable under normal warehouse conditions but should be kept in a sealed container away from strong oxidisers and direct sunlight. We ship in standard chemical packaging and can arrange custom repacking or pre-weighing at our facility, which is convenient when your downstream step requires a specific drum size or a pre-weighed lot. Because the material is a refined liquid, tight caps and drum liners matter more than desiccants; the main storage risk is slow moisture pickup at the thread, which a good seal prevents.
For sampling and small R&D orders, the 1 kg MOQ plus free-sample policy lets you run a full set of in-house GC, residual-solvent, and assay tests before scaling. For production volumes, plan around the 7-15 day delivery window and confirm Incoterms at the quoting stage (we handle FOB, CIF, EXW, and express) so freight and insurance are not a surprise on the invoice.
Related Ketones and Building Blocks
4'-Ethylpropiophenone rarely travels alone in a synthesis pipeline. Procurement teams often group it with its methyl homolog and the parent ketone on the same purchase order. The 4'-methylpropiophenone (CAS 5337-93-9) is the natural sister compound in the same series, and acetophenone (CAS 98-86-2) is the parent ketone many routes branch from. If your sequence introduces an amine or a protecting group downstream, the N-ethylmethylamine (CAS 624-78-2) and Boc anhydride (CAS 24424-99-5) we stock sit on the same bill of materials. For halogenation steps, 2-bromoacetophenone (CAS 536-38-9) is another ketone intermediate worth keeping on the same supplier list.
Why Buy From chemechemi
Shandong Deshang Chemical, the manufacturer behind chemechemi, has run foreign-trade operations since 2002 and exports to more than 140 countries. The practical benefits for a buyer are concrete: a single source for mixed intermediate orders, in-house quality control with pre-shipment reports, third-party inspection on request, and a warehouse that can hold and repack materials. For 4'-ethylpropiophenone specifically, the combination of 1 kg MOQ, free samples, and 1,000 tons/year capacity means the same supplier works for both a bench-scale validation and a full commercial campaign.
If your team is scouting a ketone intermediate for an agrochemical, pharmaceutical, or specialty organic synthesis project, start from the 4'-ethylpropiophenone (CAS 27465-51-6) product page to pull the current specification sheet, request a sample, and confirm lead time. Matching CAS 27465-51-6 on both sides of the quote is the fastest way to avoid a mislabeled intermediate slowing down a multi-step synthesis.
